UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
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Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
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Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |
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Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |
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Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |
Securities registered pursuant to Section 12(b) of the Act:
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Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).
Emerging growth company
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Item 2.02 |
Results of Operations and Financial Condition. |
On November 7, 2024, Adaptive Biotechnologies Corporation (the “Company”) issued a press release regarding the Company’s financial results for the quarter ended September 30, 2024. A copy of the press release is attached as Exhibit 99.1 and incorporated herein by reference.
The information in this Item 2.02 and the press release attached as Exhibit 99.1 hereto shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), nor shall such information be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as shall be expressly set forth by specific reference in such filing.
Item 9.01 |
Financial Statements and Exhibits. |
(d) Exhibits.
Exhibit Number |
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Description |
99.1 |
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104 |
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Cover Page Interactive Data File (embedded within the Inline XBRL document) |
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
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Adaptive Biotechnologies Corporation |
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Date: November 7, 2024 |
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By: |
/s/ Kyle Piskel |
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Kyle Piskel |
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Chief Financial Officer |
EXHIBIT 99.1
Adaptive Biotechnologies Reports Third Quarter 2024 Financial Results
SEATTLE, Nov. 07, 2024 (GLOBE NEWSWIRE) – Adaptive Biotechnologies Corporation (“Adaptive Biotechnologies”) (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease, today reported financial results for the quarter ended September 30, 2024.
“Our focus on execution and disciplined capital allocation are driving MRD growth with a clear path to profitability while we continue to advance our targeted Immune Medicine programs,” said Chad Robins, chief executive officer and co-founder of Adaptive Biotechnologies. “The increased clonoSEQ® Medicare Gapfill rate and the extension of coverage to Mantle Cell Lymphoma underscore clonoSEQ’s value to patients. I look forward to a strong finish to the year and continued progress toward our strategic goals.”
Recent Highlights
Third Quarter 2024 Financial Results
Revenue was $46.4 million for the quarter ended September 30, 2024, representing a 22% increase from the third quarter in the prior year. MRD revenue was $37.5 million for the quarter, representing a 52% increase from the third quarter in the prior year. Immune Medicine revenue was $9.0 million for the quarter, representing a 32% decrease from the third quarter in the prior year.
Operating expenses for the third quarter of 2024 were $79.1 million, compared to $88.9 million in the third quarter of the prior year, representing a decrease of 11%. MRD operating expenses for the third quarter of 2024 were $52.5 million, representing a 6% decrease from the third quarter in the prior year. Immune Medicine operating expenses for the third quarter of 2024 were $20.7 million, representing a 22% decrease from the third quarter in the prior year.
Interest and other income, net was $3.5 million for the third quarter of 2024, compared to $4.3 million in the third quarter of the prior year. Interest expense from our revenue interest purchase agreement was $2.9 million in the third quarter of 2024, compared to $3.7 million in the third quarter of the prior year.
Net loss was $32.1 million for the third quarter of 2024, compared to $50.3 million for the same period in 2023.
Adjusted EBITDA (non-GAAP) was a loss of $14.3 million for the third quarter of 2024, compared to a loss of $29.8 million for the third quarter of the prior year. MRD Adjusted EBITDA (non-GAAP) was a loss of $6.1 million for the quarter, compared to a loss of $21.6 million for the third quarter of the prior year. Immune Medicine Adjusted EBITDA (non-GAAP) was a loss of $5.2 million for the quarter, compared to a loss of $5.0 million for the third quarter of the prior year.
Cash, cash equivalents and marketable securities was $267.2 million as of September 30, 2024.
2024 Updated Financial Guidance
Adaptive Biotechnologies expects full year revenue for the MRD business to be between $143 million and $145 million, updated from the previous range between $140 million and $145 million. No revenue guidance is provided for the Immune Medicine business.
We expect full year total company operating expenses, including cost of revenue and excluding one-time costs from asset impairments and other restructuring charges, to be between $335 million and $340 million, updated from the previous range between $340 million and $350 million.
Management will provide further details on the outlook during the conference call.
Webcast and Conference Call Information
Adaptive Biotechnologies will host a conference call to discuss its third quarter 2024 financial results after market close on Thursday, November 7, 2024 at 4:30 PM Eastern Time. The conference call can be accessed at http://investors.adaptivebiotech.com. The webcast will be archived and available for replay at least 90 days after the event.
About Adaptive Biotechnologies
Adaptive Biotechnologies (“we” or “our”) is a commercial-stage biotechnology company focused on harnessing the inherent biology of the adaptive immune system to transform the diagnosis and treatment of disease. We believe the adaptive immune system is nature’s most finely tuned diagnostic and therapeutic for most diseases, but the inability to decode it has prevented the medical community from fully leveraging its capabilities. Our proprietary immune medicine platform reveals and translates the massive genetics of the adaptive immune system with scale, precision and speed. We apply our platform to partner with biopharmaceutical companies, inform drug development, and develop clinical diagnostics across our two business areas: Minimal Residual Disease (MRD) and Immune Medicine. Our commercial products and clinical pipeline enable the diagnosis, monitoring, and treatment of diseases such as cancer, autoimmune disorders, and infectious diseases. Our goal is to develop and commercialize immune-driven clinical products tailored to each individual patient.
Forward-Looking Statements
This press release contains forward-looking statements that are based on management’s beliefs and assumptions and on information currently available to management. All statements contained in this release other than statements of historical fact are forward-looking statements, including statements regarding our ability to develop, commercialize and achieve market acceptance of our current and planned products and services, our research and development efforts and other matters regarding our business strategies, use of capital, results of operations and financial position and plans and objectives for future operations.
In some cases, you can identify forward-looking statements by the words “may,” “will,” “could,” “would,” “should,” “expect,” “intend,” “plan,” “anticipate,” “believe,” “estimate,” “predict,” “project,” “potential,” “continue,” “ongoing” or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words. These statements involve risks, uncertainties and other factors that may cause actual results, levels of activity, performance or achievements to be materially different from the information expressed or implied by these forward-looking statements. These risks, uncertainties and other factors are described under "Risk Factors," "Management's Discussion and Analysis of Financial Condition and Results of Operations" and elsewhere in the documents we file with the Securities and Exchange Commission from time to time. We caution you that forward-looking statements are based on a combination of facts and factors currently known by us and our projections of the future, about which we cannot be certain. As a result, the forward-looking statements may not prove to be accurate. The forward-looking statements in this press release represent our views as of the date hereof. We undertake no obligation to update any forward-looking statements for any reason, except as required by law.
Use of Non-GAAP Financial Measure
To supplement our unaudited condensed consolidated statements of operations and unaudited condensed consolidated balance sheets, which are prepared in conformity with generally accepted accounting principles in the United States of America (“GAAP”), this press release also includes references to Adjusted EBITDA, which is a non-GAAP financial measure that we define as net loss attributable to Adaptive Biotechnologies Corporation adjusted for interest and other income, net, interest expense, income tax (expense) benefit, depreciation and amortization expense, impairment costs for long-lived assets, restructuring expense and share-based compensation expense. We define our segment Adjusted EBITDA in the same way to the extent the net loss attributable to Adaptive Biotechnologies Corporation and adjustments are allocable to each segment. We have provided reconciliations of net loss attributable to Adaptive Biotechnologies Corporation, the most directly comparable GAAP financial measure, to Adjusted EBITDA at the end of this press release.
Management uses Adjusted EBITDA, including segment Adjusted EBITDA, to evaluate the financial performance of our business and segments and to evaluate the effectiveness of our strategies. We present these figures because we believe it is frequently used by analysts, investors and other interested parties to evaluate companies in our industry and it facilitates comparisons on a consistent basis across reporting periods. Further, we believe it is helpful in highlighting trends in our operating results because it excludes items that are not indicative of our core operating performance.
Adjusted EBITDA, including segment Adjusted EBITDA, has limitations as an analytical tool and you should not consider it in isolation or as a substitute for analysis of our results as reported under GAAP. We may in the future incur expenses similar to the adjustments we make. In particular, we expect to incur meaningful share-based compensation expense in the future. Other limitations include that Adjusted EBITDA, including segment Adjusted EBITDA, does not reflect:
In addition, Adjusted EBITDA may not be comparable to similarly titled measures used by other companies in our industry or across different industries.
ADAPTIVE INVESTORS
Karina Calzadilla, Vice President, Investor Relations
201-396-1687
investors@adaptivebiotech.com
ADAPTIVE MEDIA
Erica Jones, Associate Corporate Communications Director
206-279-2423
media@adaptivebiotech.com
Adaptive Biotechnologies
Condensed Consolidated Statements of Operations
(in thousands, except share and per share amounts)
(unaudited)
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Three Months Ended September 30, |
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Nine Months Ended September 30, |
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2024 |
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2023 |
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2024 |
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2023 |
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Revenue |
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$ |
46,435 |
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$ |
37,919 |
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$ |
131,498 |
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$ |
124,492 |
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Operating expenses |
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Cost of revenue |
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16,667 |
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19,346 |
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54,035 |
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55,937 |
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Research and development |
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24,163 |
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28,533 |
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79,761 |
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93,371 |
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Sales and marketing |
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20,551 |
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20,493 |
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63,184 |
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66,673 |
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General and administrative |
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17,258 |
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20,075 |
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54,750 |
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63,208 |
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Amortization of intangible assets |
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428 |
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428 |
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1,275 |
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1,270 |
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Impairment of long-lived assets |
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— |
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— |
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7,205 |
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— |
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Total operating expenses |
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79,067 |
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88,875 |
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260,210 |
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280,459 |
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Loss from operations |
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(32,632 |
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(50,956 |
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(128,712 |
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(155,967 |
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Interest and other income, net |
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3,474 |
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4,282 |
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11,462 |
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10,918 |
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Interest expense |
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(2,939 |
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(3,652 |
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(8,628 |
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(10,788 |
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Net loss |
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(32,097 |
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(50,326 |
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(125,878 |
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(155,837 |
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Add: Net loss attributable to noncontrolling interest |
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26 |
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26 |
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78 |
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28 |
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Net loss attributable to Adaptive Biotechnologies Corporation |
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$ |
(32,071 |
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$ |
(50,300 |
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$ |
(125,800 |
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$ |
(155,809 |
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Net loss per share attributable to Adaptive Biotechnologies Corporation common shareholders, basic and diluted |
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$ |
(0.22 |
) |
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$ |
(0.35 |
) |
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$ |
(0.86 |
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$ |
(1.08 |
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Weighted-average shares used in computing net loss per share attributable to Adaptive Biotechnologies Corporation common shareholders, basic and diluted |
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147,516,398 |
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144,704,868 |
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146,908,234 |
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144,208,940 |
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Adaptive Biotechnologies
Condensed Consolidated Balance Sheets
(in thousands, except share and per share amounts)
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September 30, 2024 |
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December 31, 2023 |
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(unaudited) |
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Assets |
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Current assets |
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Cash and cash equivalents |
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$ |
38,084 |
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$ |
65,064 |
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Short-term marketable securities (amortized cost of $204,757 and $281,122, respectively) |
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205,245 |
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281,337 |
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Accounts receivable, net |
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40,814 |
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37,969 |
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Inventory |
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11,955 |
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14,448 |
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Prepaid expenses and other current assets |
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12,247 |
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11,370 |
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Total current assets |
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308,345 |
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410,188 |
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Long-term assets |
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Property and equipment, net |
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51,314 |
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68,227 |
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Operating lease right-of-use assets |
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46,530 |
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52,096 |
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Long-term marketable securities (amortized cost of $23,857) |
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23,866 |
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— |
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Restricted cash |
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2,978 |
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2,932 |
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Intangible assets, net |
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3,853 |
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5,128 |
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Goodwill |
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118,972 |
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118,972 |
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Other assets |
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2,648 |
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3,591 |
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Total assets |
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$ |
558,506 |
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$ |
661,134 |
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Liabilities and shareholders’ equity |
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Current liabilities |
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Accounts payable |
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$ |
7,351 |
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$ |
7,719 |
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Accrued liabilities |
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6,062 |
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8,597 |
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Accrued compensation and benefits |
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12,337 |
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13,685 |
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Current portion of operating lease liabilities |
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10,021 |
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9,384 |
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Current portion of deferred revenue |
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51,856 |
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48,630 |
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Total current liabilities |
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87,627 |
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88,015 |
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Long-term liabilities |
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Operating lease liabilities, less current portion |
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81,804 |
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89,388 |
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Deferred revenue, less current portion |
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32,781 |
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44,793 |
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Revenue interest liability, net |
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132,700 |
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130,660 |
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Other long-term liabilities |
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20 |
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— |
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Total liabilities |
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334,932 |
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352,856 |
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Commitments and contingencies |
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Shareholders’ equity |
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Preferred stock: $0.0001 par value, 10,000,000 shares authorized at September 30, 2024 and December 31, 2023; no shares issued and outstanding at September 30, 2024 and December 31, 2023 |
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— |
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— |
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Common stock: $0.0001 par value, 340,000,000 shares authorized at September 30, 2024 and December 31, 2023; 147,561,586 and 145,082,271 shares issued and outstanding at September 30, 2024 and December 31, 2023, respectively |
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14 |
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14 |
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Additional paid-in capital |
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1,493,394 |
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1,452,502 |
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Accumulated other comprehensive gain |
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497 |
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215 |
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Accumulated deficit |
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(1,270,132 |
) |
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(1,144,332 |
) |
Total Adaptive Biotechnologies Corporation shareholders’ equity |
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223,773 |
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|
308,399 |
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Noncontrolling interest |
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(199 |
) |
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(121 |
) |
Total shareholders’ equity |
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223,574 |
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308,278 |
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Total liabilities and shareholders’ equity |
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$ |
558,506 |
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$ |
661,134 |
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Adjusted EBITDA
The following is a reconciliation of net loss attributable to Adaptive Biotechnologies Corporation, the most directly comparable GAAP financial measure, to Adjusted EBITDA for the periods presented (in thousands, unaudited):
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Three Months Ended September 30, |
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Nine Months Ended September 30, |
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2024 |
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2023 |
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2024 |
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2023 |
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Net loss attributable to Adaptive Biotechnologies Corporation |
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$ |
(32,071 |
) |
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$ |
(50,300 |
) |
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$ |
(125,800 |
) |
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$ |
(155,809 |
) |
Interest and other income, net |
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(3,474 |
) |
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(4,282 |
) |
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(11,462 |
) |
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(10,918 |
) |
Interest expense |
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2,939 |
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3,652 |
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8,628 |
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|
|
10,788 |
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Depreciation and amortization expense |
|
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4,591 |
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|
|
5,763 |
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|
|
14,808 |
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|
|
16,839 |
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Impairment of long-lived assets |
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|
— |
|
|
|
— |
|
|
|
7,205 |
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|
|
— |
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Restructuring expense |
|
|
193 |
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|
|
— |
|
|
|
1,917 |
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|
|
— |
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Share-based compensation expense |
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13,522 |
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|
|
15,336 |
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|
40,778 |
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|
|
47,352 |
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Adjusted EBITDA |
|
$ |
(14,300 |
) |
|
$ |
(29,831 |
) |
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$ |
(63,926 |
) |
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$ |
(91,748 |
) |
Segment Information (Including Segment Adjusted EBITDA)
The following tables set forth our segment information for the three and nine months ended September 30, 2024 and 2023, respectively (in thousands, unaudited):
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Three Months Ended September 30, 2024 |
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MRD |
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Immune Medicine |
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Unallocated Corporate |
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Total |
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Revenue |
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$ |
37,470 |
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|
$ |
8,965 |
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|
$ |
— |
|
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$ |
46,435 |
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Operating expenses |
|
|
52,538 |
|
|
|
20,689 |
|
|
|
5,840 |
|
|
|
79,067 |
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Adjusted EBITDA |
|
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(6,120 |
) |
|
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(5,212 |
) |
|
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(2,968 |
) |
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(14,300 |
) |
Reconciliation of Net Loss to Adjusted EBITDA: |
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Net loss |
|
$ |
(15,068 |
) |
|
$ |
(11,724 |
) |
|
$ |
(5,305 |
) |
|
$ |
(32,097 |
) |
Net loss attributable to noncontrolling interest |
|
|
— |
|
|
|
— |
|
|
|
26 |
|
|
|
26 |
|
Net loss attributable to Adaptive Biotechnologies Corporation |
|
|
(15,068 |
) |
|
|
(11,724 |
) |
|
|
(5,279 |
) |
|
|
(32,071 |
) |
Interest and other income, net |
|
|
— |
|
|
|
— |
|
|
|
(3,474 |
) |
|
|
(3,474 |
) |
Interest expense |
|
|
— |
|
|
|
— |
|
|
|
2,939 |
|
|
|
2,939 |
|
Depreciation and amortization expense |
|
|
2,428 |
|
|
|
1,728 |
|
|
|
435 |
|
|
|
4,591 |
|
Restructuring expense |
|
|
167 |
|
|
|
26 |
|
|
|
— |
|
|
|
193 |
|
Share-based compensation expense |
|
|
6,353 |
|
|
|
4,758 |
|
|
|
2,411 |
|
|
|
13,522 |
|
Adjusted EBITDA |
|
$ |
(6,120 |
) |
|
$ |
(5,212 |
) |
|
$ |
(2,968 |
) |
|
$ |
(14,300 |
) |
|
|
Three Months Ended September 30, 2023 |
|
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|
|
MRD |
|
|
Immune Medicine |
|
|
Unallocated Corporate |
|
|
Total |
|
||||
Revenue |
|
$ |
24,668 |
|
|
$ |
13,251 |
|
|
$ |
— |
|
|
$ |
37,919 |
|
Operating expenses |
|
|
55,977 |
|
|
|
26,400 |
|
|
|
6,498 |
|
|
|
88,875 |
|
Adjusted EBITDA |
|
|
(21,616 |
) |
|
|
(4,986 |
) |
|
|
(3,229 |
) |
|
|
(29,831 |
) |
Reconciliation of Net Loss to Adjusted EBITDA: |
|
|
|
|
|
|
|
|
|
|
|
|
||||
Net loss |
|
$ |
(31,309 |
) |
|
$ |
(13,148 |
) |
|
$ |
(5,869 |
) |
|
$ |
(50,326 |
) |
Net loss attributable to noncontrolling interest |
|
|
— |
|
|
|
— |
|
|
|
26 |
|
|
|
26 |
|
Net loss attributable to Adaptive Biotechnologies Corporation |
|
|
(31,309 |
) |
|
|
(13,148 |
) |
|
|
(5,843 |
) |
|
|
(50,300 |
) |
Interest and other income, net |
|
|
— |
|
|
|
— |
|
|
|
(4,282 |
) |
|
|
(4,282 |
) |
Interest expense |
|
|
— |
|
|
|
— |
|
|
|
3,652 |
|
|
|
3,652 |
|
Depreciation and amortization expense |
|
|
2,489 |
|
|
|
2,546 |
|
|
|
728 |
|
|
|
5,763 |
|
Share-based compensation expense |
|
|
7,204 |
|
|
|
5,616 |
|
|
|
2,516 |
|
|
|
15,336 |
|
Adjusted EBITDA |
|
$ |
(21,616 |
) |
|
$ |
(4,986 |
) |
|
$ |
(3,229 |
) |
|
$ |
(29,831 |
) |
|
|
Nine Months Ended September 30, 2024 |
|
|||||||||||||
|
|
MRD |
|
|
Immune Medicine |
|
|
Unallocated Corporate |
|
|
Total |
|
||||
Revenue |
|
$ |
105,380 |
|
|
$ |
26,118 |
|
|
$ |
— |
|
|
$ |
131,498 |
|
Operating expenses |
|
|
170,785 |
|
|
|
70,663 |
|
|
|
18,762 |
|
|
|
260,210 |
|
Adjusted EBITDA |
|
|
(34,668 |
) |
|
|
(19,172 |
) |
|
|
(10,086 |
) |
|
|
(63,926 |
) |
Reconciliation of Net Loss to Adjusted EBITDA: |
|
|
|
|
|
|
|
|
|
|
|
|
||||
Net loss |
|
$ |
(65,405 |
) |
|
$ |
(44,545 |
) |
|
$ |
(15,928 |
) |
|
$ |
(125,878 |
) |
Net loss attributable to noncontrolling interest |
|
|
— |
|
|
|
— |
|
|
|
78 |
|
|
|
78 |
|
Net loss attributable to Adaptive Biotechnologies Corporation |
|
|
(65,405 |
) |
|
|
(44,545 |
) |
|
|
(15,850 |
) |
|
|
(125,800 |
) |
Interest and other income, net |
|
|
— |
|
|
|
— |
|
|
|
(11,462 |
) |
|
|
(11,462 |
) |
Interest expense |
|
|
— |
|
|
|
— |
|
|
|
8,628 |
|
|
|
8,628 |
|
Depreciation and amortization expense |
|
|
7,733 |
|
|
|
5,777 |
|
|
|
1,298 |
|
|
|
14,808 |
|
Impairment of long-lived assets |
|
|
2,819 |
|
|
|
4,386 |
|
|
|
— |
|
|
|
7,205 |
|
Restructuring expense |
|
|
1,195 |
|
|
|
722 |
|
|
|
— |
|
|
|
1,917 |
|
Share-based compensation expense |
|
|
18,990 |
|
|
|
14,488 |
|
|
|
7,300 |
|
|
|
40,778 |
|
Adjusted EBITDA |
|
$ |
(34,668 |
) |
|
$ |
(19,172 |
) |
|
$ |
(10,086 |
) |
|
$ |
(63,926 |
) |
|
|
Nine Months Ended September 30, 2023 |
|
|||||||||||||
|
|
MRD |
|
|
Immune Medicine |
|
|
Unallocated Corporate |
|
|
Total |
|
||||
Revenue |
|
$ |
71,977 |
|
|
$ |
52,515 |
|
|
$ |
— |
|
|
$ |
124,492 |
|
Operating expenses |
|
|
170,946 |
|
|
|
88,753 |
|
|
|
20,760 |
|
|
|
280,459 |
|
Adjusted EBITDA |
|
|
(71,081 |
) |
|
|
(11,149 |
) |
|
|
(9,518 |
) |
|
|
(91,748 |
) |
Reconciliation of Net Loss to Adjusted EBITDA: |
|
|
|
|
|
|
|
|
|
|
|
|
||||
Net loss |
|
$ |
(98,969 |
) |
|
$ |
(36,236 |
) |
|
$ |
(20,632 |
) |
|
$ |
(155,837 |
) |
Net loss attributable to noncontrolling interest |
|
|
— |
|
|
|
— |
|
|
|
28 |
|
|
|
28 |
|
Net loss attributable to Adaptive Biotechnologies Corporation |
|
|
(98,969 |
) |
|
|
(36,236 |
) |
|
|
(20,604 |
) |
|
|
(155,809 |
) |
Interest and other income, net |
|
|
— |
|
|
|
— |
|
|
|
(10,918 |
) |
|
|
(10,918 |
) |
Interest expense |
|
|
— |
|
|
|
— |
|
|
|
10,788 |
|
|
|
10,788 |
|
Depreciation and amortization expense |
|
|
6,812 |
|
|
|
7,907 |
|
|
|
2,120 |
|
|
|
16,839 |
|
Share-based compensation expense |
|
|
21,076 |
|
|
|
17,180 |
|
|
|
9,096 |
|
|
|
47,352 |
|
Adjusted EBITDA |
|
$ |
(71,081 |
) |
|
$ |
(11,149 |
) |
|
$ |
(9,518 |
) |
|
$ |
(91,748 |
) |